Top 10 influencers with the largest audiences on Instagram and TikTok in the United States (September 2025)
Every month we analyze who leads the social media conversation. This followers radar highlights the profiles with the biggest audiences on Instagram and TikTok — always focusing on what really matters: how many followers they actually have in the U.S.
What does this ranking measure?
The ranking is based on data from Kolsquare, identifying the profiles with the largest number of followers in the U.S. It’s not just about global reach — the focus is on who has a truly active and localized community in the American market.
That’s why we only feature creators with significant audiences in the country.
Top 10 followers Instagram U.S.
Top 10 – Instagram (september 2025)
1. Cardi B
The rapper continues to shape U.S. pop culture. Her mix of music, humor, and social media presence turns every post into a national conversation. She remains a key voice for both the Latino and urban communities.
2. Kevin Hart
The comedian has turned his profile into a megaphone for everything he does: movies, stand-up, sports, and fitness. His upbeat tone and nonstop activity make him recognizable to both mainstream audiences and younger fans.
3. LeBron James
Beyond basketball, LeBron has become a social and cultural leader. His influence extends to media projects, activism, and business. This summer he was in the spotlight with Team USA at the Olympic Games.
4. Zendaya
After the success of Dune: Part Two and with fans awaiting the new season of Euphoria, Zendaya remains at the center of cultural conversation. Her profile blends fashion, film, and lifestyle, making her one of Gen Z’s strongest icons in the U.S.
5. Drake
The Canadian rapper is nearly omnipresent in urban music. Each release instantly trends and his memes spread beyond the industry. His latest U.S. tour reinforced his unmatched status.
6. Ellen DeGeneres
Although no longer hosting her iconic talk show, Ellen remains a household name. Her long-built image of humor and warmth still resonates with millions. She maintains an active presence that keeps her audience engaged.
7. Chris Brown
The singer continues to draw a massive fan base in R&B and hip hop. Despite ongoing controversy, his music remains relevant and sparks conversation. His latest U.S. tour once again proved his lasting appeal.
8. MrBeast
The YouTuber has broken barriers across platforms with extreme challenges and philanthropy. This month he went viral again with a survival challenge that gained millions of views. He’s one of the creators who best understands cross-platform storytelling.
9. IShowSpeed
The streamer is one of the most explosive digital phenomena in recent years. His chaotic, unfiltered style resonates with young audiences. This summer, his Euro Cup livestreams made headlines and dominated U.S. social media.
10. Snoop Dogg
A legend who has adapted to every era. From rap to television and unexpected collabs, Snoop remains a cultural icon across generations. Recent partnerships with brands and video games only strengthen that status.
Top 10 followers TikTok U.S.
Top 10 – TikTok (september 2025)
1. KallMeKris
The Canadian creator is one of TikTok’s biggest comedy figures. Her short sketches and recurring characters connect with audiences looking for quick, relatable entertainment. In the U.S., she ranks among the most consistently viral profiles.
2. Gordon Ramsay
The world’s most famous chef also dominates TikTok. His mix of harsh critiques, cooking challenges, and collabs with younger creators keeps him fresh. In the U.S., he bridges generations from foodies to entertainment fans.
3. Kevin Hart
Hart is also a phenomenon on TikTok: his short-form humor and creator collabs fit the platform perfectly. TikTok lets him show a more spontaneous and viral side compared to Instagram.
4. Lizzo
The singer resonates with communities that value authenticity and diversity. Her body positivity message and vibrant style make her a cultural reference point. This summer she returned with new music and international tours.
5. Kylie Jenner
Part of the Kardashian-Jenner clan, Kylie has built a strong standalone digital presence. TikTok is the stage for her personal brand and cosmetics empire. Recent Kylie Cosmetics campaigns highlight her influence.
6. Billie Eilish
An icon for her generation, Billie strengthens that bond on TikTok. Following the release of her new album this spring, she has stayed at the center of the music conversation. She mixes artistry with an authentic narrative that resonates widely.
7. Avani
Part of TikTok’s first wave of creators, Avani keeps her presence strong with a distinct aesthetic and personal style. She continues to connect with younger audiences through frequent collabs.
8. Larray
Known for blending sharp humor with music, Larray is highly recognizable. His content connects queer fandoms and meme culture. Recent collabs with other creators have amplified his reach.
9. Celina Spooky Boo
Her eccentric, authentic humor has made her one of TikTok’s most beloved creators. Her comedy videos often go viral, representing the platform’s alternative, relatable side.
10. JoJo Siwa
From child star to multiplatform creator, JoJo maintains a loyal fan base. TikTok is her main channel to reach longtime followers and new generations. Recent reality show appearances and live performances boosted her cultural visibility.
Why does this ranking matter?
These profiles are key to understanding what content U.S. audiences consume and which figures are driving the most impact. For brands, these insights are essential to connect with audiences and improve any digital strategy.
Want to dig deeper? We can provide you with more audience data or help shape your next campaign.
Contact us: info@playthegame.com
All the data in this article was sourced from Kolsquare. At Play The Game Agency, we specialize in analyzing and understanding these trends to design the best strategies and solutions for our clients and partners. If you’d like to explore how we can help you leverage these opportunities, don’t hesitate to get in touch.
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